Up Syndrome (2000)

University of Texas student Duane Graves chronicles his charismatic childhood chum Rene Moreno, a San Antonio native with Down Syndrome, in this playful, stirring, remarkably unique portrait documentary.

If you liked Up Syndrome, you might also like…

92% match

Come See Me in the Good Light

2025

85% match

Anna Nicole Smith: You Don't Know Me

2023

87% match

Chadwick Boseman: A Tribute for a King

2020

81% match

The Class of ‘92

2013

78% match

The Curse of the Dragon

1993

77% match

My Mom Jayne

2025

70% match

Directed by John Ford

1971

64% match

Naqoyqatsi

2002

65% match

As I Was Moving Ahead Occasionally I Saw Brief Glimpses of Beauty

2000

60% match

Drew: The Man Behind the Poster

2013

60% match

I Am Heath Ledger

2017

60% match

The Curious Birth of Benjamin Button

2009

60% match

Birth of the Living Dead

2013

60% match

The U.S. vs. John Lennon

2006

60% match

The Assassination of Jesse James: Death of an Outlaw

2008

60% match

To Kill a Tiger

2023

60% match

Charlie: The Life and Art of Charles Chaplin

2003

60% match

McQueen

2018

60% match

Avatar: The Deep Dive - A Special Edition of 20/20

2022

60% match

Trainwreck: The Real Project X

2025